Question

What is the amount of oxygen supply to tissues through every hundred ml of blood under normal physiological condition

Answer 1

Answer:

Haemoglobin has a maximum theoretical oxygen-carrying capacity of 1.39 ml O2 g−1 Hb (known as Hüfner's constant), and therefore, a theoretical maximum oxygen capacity of 20.85 ml O2 100 ml−1 blood at a ‘normal’ haemoglobin concentration of 15 g dl−1 (range 13.5–18.0 in men, 11.5–16.0 in women). However, due in part to the existence of abnormal forms of haemoglobin such as methaemoglobin and carboxyhaemoglobin, which reduce the oxygen-carrying capacity of haemoglobin, empirically this value seems to be closer to 1.31 ml O2 g−1 Hb.5,11 Haemoglobin oxygen saturation is a percentage expression of the number of oxygen binding sites occupied out of the maximum number of oxygen binding sites available.

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