Question

what is the cause of expression of haemophilia disease only at homozygous condition​

Answer 1

Answer:

These include (i) skewed inactivation of the X chromosome leading to predominant expression of the mutated allele as a result of a preferential inactivation of the X chromosome with the wild-type F8 gene,[ (ii) Turner syndrome, (iii) translocation or (iv) males with a female phenotype due to mutation