Biology, asked by luthra1515, 11 months ago

What is the cause of sickle cell anaemia ?

Answers

Answered by nain31
4
ANSWER....

THE SICKLE CELL ANEMIA IS CAUSED DUE TO MUTATION OF GENES OR CHROMOSOMES.


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Answered by zander07
1
In sickle cell anaemia there is substitution of Glutamic acid by valanine at sixth position of beta globin chain of haemoglobin molecule.
The mutant haemoglobin molecule undergoes polymerisation under low oxygen tension causing change in shape of RBC from biconcave to Sickle shaped.
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