Question

what is the colchicine induced inhibitory effect on mitosis​

Answer 1

Early antibody reversal restored cells to the diploid state, whereas delayed reversal resulted in a time-dependent increase in polyploidy. Colchicine-induced polyploidy and chromosomal aberrations may be the basis for both colchicine toxicity and the time-dependent increase in irreversibility of colchicine effects.

Answer 2

Referred to the attachment....