What is the connecting link between glycolysis and kreb cycle
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Acetyl-CoA, main product of the Pyruvate Dehydrogenase Complex in aerobic respiration, starts the Krebs cycle. (An irreversible reaction that islink between glycolysis and the citric acid cycle.) The mechanism of the synthesis of acetyl coenzyme A from pyruvate requires five coenzymes and three enzymes.
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The reaction linking glycolysis with Krebs cycle is called LINK REACTION.
It involves an enzyme complex with 3 enzymes( pyruvate dehydrogenase, dihydro-lipoyl transacetylase and dihydro-lipoyl dehydrogenase) and 5 co enzymes like FAD, NAD, Thiamine, CoA, etc
This enzyme complex converts pyruvate (3 carbon) to acetyl CoA ( 2 carbon)
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