Question

what is the denaturion of protein

Answer 1

Denaturation is a process in which proteins ornucleic acids lose the quaternary structure,tertiary structure and secondary structurewhich is present in their native state, by application of some external stress or compound such as a strong acid or base, a concentrated inorganic salt, an organicsolvent (e.g., alcohol or chloroform), radiation or heat. If proteins in a living cell are denatured, this results in disruption of cell activity and possibly cell death. Protein denaturation is also a consequence of cell death. Denatured proteins can exhibit a wide range of characteristics, fromconformational change and loss of solubility to aggregation due to the exposure ofhydrophobic groups. Denatured proteins lose their 3D structure and therefore cannot function.

Protein folding is key to whether a globular protein or a membrane protein can do its job correctly. It must be folded into the right shape to function. But hydrogen bonds, which play a big part in folding, are rather weak, and it doesn't take much heat, acidity, varying salt concentrations, or other stress to break some and form others, denaturing the protein. This is one reason why tight homeostasis isphysiologically necessary in many life forms.

This concept is unrelated to denatured alcohol, which is alcohol that has been mixed with additives to make it unsuitable for human consumption.

Answer 2

Denaturation is a process in which proteins or nucleic acids loose the quaternary structure , tertiary structure and secondary structure , which is present in their native state , by application of some external stress or compound such as strong acid or base , radiation of heat.Hope it helps.