Question

what is the diameter of micro and narrow bore in hplc?

Answer 1

narrow-bore and micro-bore columns in liquid chromatography. Currently, there is a strong trend in liquid chromatography to reduce the size of the chromatographic column. This field has attracted a number of active groups, each pursuing significantly different aims. In fact, one could distinguish two different approaches: the use of conventional packed columns having a diameter smaller than 4–5 mm, which has been the standard since the inception of modern column liquid chromatography in the mid 1960s till the present, and attempts to develop entirely different column types using capillary tubes and related techniques. The motivation lying behind the development work in the capillary column field is to find a breakthrough in column performance, a way of achieving a very high resolving power within a reasonable period of time. In addition, the chapter also describes the basic properties of the different kinds of columns and their performances and limitations from a theoretical standpoint, and defines some of the specifications for the equipment associated with them.

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