What is the difference between bone and magnesim alloy biodegradble material?
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Answer:
As the largest dynamic biological tissue in the body, bones are composed of inorganic minerals and metabolically active cells surrounded by a large volume of extracellular matrix, and they form a rigid framework that has an irreplaceable role in maintaining life activities, including supporting the body and protecting visceral organs . Surgical treatment of bone injuries has become common, where there are millions of bone injury patients in emergency departments worldwide each year due to involvement in vigorous athletic activities, social instability, traffic accidents, and prolonged human lifespan . Bone defects, mainly induced by traumatic avulsions, sequelae of infection-induced bony sequestration, congenital malformations, or neoplastic resections, confront us with an extreme challenge for reconstructive surgery. The need to induce bone regeneration to repair structural bone deficiencies has inspired research on and development of a vast number of bone repair materials.
Magnesium (Mg) alloys have a reputation for being revolutionary biodegradable metal materials in orthopedic applications due to their good biocompatibility, biodegradability, and acceptable mechanical properties . The fourth most plentiful cation in the human body, Mg is an element essential in many metabolic processes and is primarily stored in bone tissue. Mg is taken into the body daily in substantial amounts, stimulates the growth of bone cells, and accelerates the healing of bone tissue. Mg alloys are degraded in vivo due to the presence of Cl− in the physiological environment, thereby eliminating the need for secondary surgeries to remove the implant