What is the difference between carboxymethyl cellulose and hydroxypropylmethylcellulose?
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BACKGROUND: Hydroxypropyl methylcellulose (HPMC), a popular gonioscopic solution, can cause discomfort and blurred vision. These side effects have been attributed to the preservative benzalkonium chloride (BAK). Carboxymethylcellulose (CMC), an unpreserved, viscous solution, might well provide adequate patient comfort and cushioning during gonioscopy without producing blur or irritation.
METHODS: The effects of CMC and HPMC during gonioscopy were evaluated in 55 human subjects. Corneal staining, comfort, subjective vision, and measured visual acuity (VA) were assessed.
RESULTS: In comparison with HPMC, CMC effected less corneal staining, greater comfort, and better vision after the procedure,
CONCLUSION: CMC proved to be a viable and superior alternative to HPMC as a gonioscopic solution.
PMID
8843126 [Indexed for MEDLINE]
Similar articles
[In vitro evaluation of corneal damages after instillation of eye drops using rat debrided corneal epithelium: changes of corneal damage due to benzalkonium chloride by addition of thickening agents].Nagai N, et al. Yakugaku Zasshi. 2012.Unpreserved carboxymethylcellulose artificial tears evaluated in patients with keratoconjunctivitis sicca.
Randomized controlled trial
Grene RB, et al. Cornea. 1992.A comparison of the effect of refresh plus and bion tears on dry eye symptoms and ocular surface health in myopic LASIK patients.Albietz JM, et al. CLAO J. 2002.Bringing comfort to the masses: a novel evaluation of comfort agent solution properties.
Review article
White CJ, et al. Cont Lens Anterior Eye. 2014.Gonioscopy: evaluation of the anterior chamber angle. Part II.
Review article
Prokopich CL, et al. Ophthalmic Physiol Opt. 1997.
METHODS: The effects of CMC and HPMC during gonioscopy were evaluated in 55 human subjects. Corneal staining, comfort, subjective vision, and measured visual acuity (VA) were assessed.
RESULTS: In comparison with HPMC, CMC effected less corneal staining, greater comfort, and better vision after the procedure,
CONCLUSION: CMC proved to be a viable and superior alternative to HPMC as a gonioscopic solution.
PMID
8843126 [Indexed for MEDLINE]
Similar articles
[In vitro evaluation of corneal damages after instillation of eye drops using rat debrided corneal epithelium: changes of corneal damage due to benzalkonium chloride by addition of thickening agents].Nagai N, et al. Yakugaku Zasshi. 2012.Unpreserved carboxymethylcellulose artificial tears evaluated in patients with keratoconjunctivitis sicca.
Randomized controlled trial
Grene RB, et al. Cornea. 1992.A comparison of the effect of refresh plus and bion tears on dry eye symptoms and ocular surface health in myopic LASIK patients.Albietz JM, et al. CLAO J. 2002.Bringing comfort to the masses: a novel evaluation of comfort agent solution properties.
Review article
White CJ, et al. Cont Lens Anterior Eye. 2014.Gonioscopy: evaluation of the anterior chamber angle. Part II.
Review article
Prokopich CL, et al. Ophthalmic Physiol Opt. 1997.
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