What is the difference between genotype and phenotype?
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A genotype refers to the genetic characteristics of an organism. A phenotype refers to the physical characteristics. For example, having blue eyes (an autosomal recessive trait) is a phenotype; lacking the gene for brown eyes is a genotype. Dysferlin deficiency will only cause muscle weakness (phenotype) if a person has two defective copies of the dysferlin gene (genotype). The genotype of two defective dysferlin genes is associated with two different phenotypes, the symptoms of LGMD2B or of Miyoshi Myopathy.
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