What is the difference between Rough and
Smooth Endoplasmic Reticulum?
Answers
Rough Endoplasmic Reticulum (RER) Smooth Endoplasmic Reticulum (SER)
It possesses ribosomes attached to its membrane. It does not have ribosomes on its membrane.
Formed of cisternae and a few tubules. Formed of vesicles and tubules.
It participates in the synthesis of enzymes and proteins. Synthesises glycogen, lipids and steroids.
It helps in the formation of lysosomes. Gives rise to Spherosomes/ Oleosomes
It is internal and connected with the nuclear envelope. It is peripheral and may be connected to plasmalemma.
Ribophorins are present and help ribosomes attach to ER Devoid of Ribophorins.
It might develop from the nuclear envelope Develops from Rough Endoplasmic Reticulum
Provides proteins and lipids for Golgi apparatus. Provides vesicles for cis-face of Golgi apparatus.
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Overview :
The difference lies between the two is that the Smooth Endoplasmic Reticulum is not bounded by the ribosomes and is known for storing the lipids and proteins. Meanwhile, the Rough Endoplasmic Reticulum is bounded by the ribosomes and store proteins.
Smooth ER- is found near the cell membrane.
Rough ER - is found near the cytoplasm.
Smooth ER - has ribosomes.
Rough ER - doesn't have ribosomes.
Smooth ER - produces Lipids and Proteins.
Rough ER - produces only Proteins.