what is the DNA rpackaging
Answers
DNA packaging :
Length of DNA double helix molecule, in
a typical mammalian cell is approximately
2.2 meters. (This can be worked out simply by
multiplying the total number of base pairs with
distance between the consecutive base pairs).
Approximate size of a typical nucleus is 10-6
m. How this long DNA molecule can be then
accommodated in such a small nucleus? It,
therefore, must be condensed, coiled and super
coiled to fit inside such small nucleus
The process starts when DNA is wrapped around special protein molecules called histones. The combined loop of DNA and protein is called a nucleosome. Next the nucleosomes are packaged into a thread, which is sometimes described as "beads on a string". The end result is a fiber known as chromatin.
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