what is the folding code for denatured proteins?And can we predict the native structure of a portion from its amino acid sequence precisely?
Answers
Answer:
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Answer:
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Explanation:
The Folding CodeEdit
In the late 1980s, scientists discovered that there is a sequence of amino acid code that folds proteins in a particular way. The starting point of protein folding is indeed the primary structure (the sequence of amino acids), also known as denatured state of the protein.
Protein structure prediction is the inference of the three-dimensional structure of a protein from its amino acid sequence—that is, the prediction of its folding and its secondary and tertiary structure from its primary structure. Structure prediction is fundamentally different from the inverse problem of protein design. Protein structure prediction is one of the most important goals pursued by bioinformatics and theoretical chemistry; it is highly important in medicine (for example, in drug design) and biotechnology (for example, in the design of novel enzymes). Every two years, the performance of current methods is assessed in the CASP experiment (Critical Assessment of Techniques for Protein Structure Prediction)