Question

what is the function of dna polymerase 1

Answer 1

DNA polymerase is an enzyme that synthesizes DNA molecules from deoxyribonucleotides, the building blocks of DNA. These enzymes are essential for DNA replication and usually work in pairs to create two identical DNA strands from a single original DNA molecule. During this process, DNA polymerase "reads" the existing DNA strands to create two new strands that match the existing ones.

Answer 2

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Here is your answer,

$dna \: polymerase \: 1 =$

#DNA polymerase I (or Pol I) is an enzyme that participates in the process of prokaryotic DNA replication.

#These enzymes are specially designed to help in the replication of DNA, but each has a unique and necessary function. Pol III is the primary enzyme in DNA replication serving to read the template strand (working on both the leading and lagging strand) and incorporate the correct base pair.

#Pol I possesses four enzymatic activities:

1) A 5'→3' (forward) DNA-Dependent DNA polymerase activity, requiring a 3' primer site and a template strand

2) A 3'→5' (reverse) exonuclease activity that mediates proofreading

3) A 5'→3' (forward) exonuclease activity mediating nick translation during DNA repair.

4) A 5'→3' (forward) RNA-Dependent DNA polymerase activity. Pol I operates on RNA templates with considerably lower efficiency (0.1–0.4%) than it does DNA templates, and this activity is probably of only limited biological significance.

#DNA polymerase I in prokaryotes is far from irrelevant, however. This enzyme serves a host of “Clean-up” function during replication, recombination and repair. These special functions are enhanced by an additional enzymatic activity of DNA polymerase I, a 5’->3’ exonuclease activity. This activity is distinct from the 3’->5’ proofreading exonuclease and is located in a distinct structural domain that can be separated from the enzyme by mild protease treatment. When the new Okazaki fragment is complete, the RNA primer is removed by DNA polymerase-I and is replaced with DNA by the sea enzyme.

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