What is the Henderson-Hasselbalch equation? How is it used in chemistry?
Answers
Answer:
The Henderson–Hasselbalch equation relates the pH of a solution containing a mixture of the two components to the acid dissociation constant, Ka, and the concentrations of the species in solution.
As may be seen from the Henderson–Hasselbalch equation, when the pH of the solution equals the pK′ of the buffer, [conjugate base] = [acid], the buffer can respond equally to both added acid and added base. Similar to weak acid dissociation reaction, Henderson–Hasselbalch relationship for weak base can be applied.
A buffer solution (more precisely, pH buffer or hydrogen ion buffer) is an aqueous solution consisting of a mixture of a weak acid and its conjugate base, or vice versa. ... Buffer solutions are used as a means of keeping pH at a nearly constant value in a wide variety of chemical applications.