What is the international view and indian view about acrylamide?
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Acrylamide (C3
H5
NO; 2-propenamide), is a colourless, non-volatile
crystalline solid, soluble in water and has a molecular weight of 71.08
kDa [1,2]. It is produced commercially by hydrolyzing acrylonitrile
using nitrile hydrase and exists in two forms: monomer and polymer.
It is used to produce polyacrylamide polymer, which find many
uses as a coagulant in waste water treatment and clarifying drinking
water, grouting agents for the construction of dam foundations and
tunnels and as electrophoresis gels. In 1994, the International Agency
for Research on Cancer (IARC) classified acrylamide as a potential
carcinogen to humans (Group 2A) based on its carcinogenicity in
rodents. This classification was endorsed by the WHO Consultation
in 2002. The single (monomer) form of acrylamide, is recently
discovered to be present in food, which is toxic to the nervous system.
A carcinogen in rodents, and a suspected carcinogen in humans cause
gene mutation and DNA damage [2,3-12]. It is probably always been
present in cooked foods and cigarette smoke. However, the presence of
acrylamide in foods was first reported by the Swedish National Food
Administration (SNFA) in 2002. It is considered as the important heat-
induced process contaminants formed mostly in potato, cereal and
bakery products, respectively by the heat treatment.
H5
NO; 2-propenamide), is a colourless, non-volatile
crystalline solid, soluble in water and has a molecular weight of 71.08
kDa [1,2]. It is produced commercially by hydrolyzing acrylonitrile
using nitrile hydrase and exists in two forms: monomer and polymer.
It is used to produce polyacrylamide polymer, which find many
uses as a coagulant in waste water treatment and clarifying drinking
water, grouting agents for the construction of dam foundations and
tunnels and as electrophoresis gels. In 1994, the International Agency
for Research on Cancer (IARC) classified acrylamide as a potential
carcinogen to humans (Group 2A) based on its carcinogenicity in
rodents. This classification was endorsed by the WHO Consultation
in 2002. The single (monomer) form of acrylamide, is recently
discovered to be present in food, which is toxic to the nervous system.
A carcinogen in rodents, and a suspected carcinogen in humans cause
gene mutation and DNA damage [2,3-12]. It is probably always been
present in cooked foods and cigarette smoke. However, the presence of
acrylamide in foods was first reported by the Swedish National Food
Administration (SNFA) in 2002. It is considered as the important heat-
induced process contaminants formed mostly in potato, cereal and
bakery products, respectively by the heat treatment.
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