What is the link between telomerase and hiv?
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The effect of human immunodeficiency virus type 1 (HIV-1) on telomerase activity in peripheral blood lymphocytes (The effect of human immunodeficiency virus type 1 (HIV-1) on telomerase activity in peripheral blood lymphocytes (PBL) was examined. Telomerase is an enzyme that is involved in mechanisms that control cell life span and replicative potential.) was examined. Telomerase is an enzyme that is involved in mechanisms that control cell life span and replicative potential.
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Telomerase inhibition has been considered a possible mechanism by which antiretroviral treatment in HIV/AIDS causes accelerated aging. ... Early in the HIV/AIDS epidemic, it was discovered that the effect of NRTIs, including AZT, caused progressive telomere shortening in immortalized B- and T-cell line
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