Question

What is the major product in the following reaction :RX+NaOR'​

Answer 1

Answer:

The major product of the reaction is given by the option (B). In the first step,acid chloride is more reactive than alkyl halide.

Answer 2

Alkyl Halides react with Sodium alkoxide to yield ethers as major products.

• Ethers can be prepared by reacting alkyl halides with alkoxy ions in presence of an inorganic base.
• This process is termed Williamson's synthesis of ethers.
• The mechanism involves $S_{N} 2$ nucleophilic substitution, where the alkoxide ion acts as the attacking nucleophile and the halide ion is the leaving group.
• The attacking nucleophile attacks the carbon from the backside forming a transition state, followed by the removal of halide.
• Thus the reaction involves the formation of a C-O bond and a cleavage of the C-X bond.
• The general reaction can be depicted as below:

                           $RX + NaOR^{'}$  → $ROR^{'} + NaX$