Question

What is the metabolic fate of pyruvate?

Answer 1

Well, the fate of pyruvate depend on two factor whether oxygen is present or not. In the presence of oxygen (aerobic condition) pyruvate is converted to acetyl-CoA by the enzyme pyruvate dehydrogenasewhich enters the TCA or Kerb cycle where large (most) of ATP moleculesis generated.neww

Answer 2

Answer:

The oxidation of glucose and, to a much smaller degree, the deamination of alanine, generates pyruvate, which has four metabolic fates: (1) enter mitochondria and be oxidized to acetyl-CoA via pyruvate dehydrogenase. (2) Enter mitochondria and be carboxylated to form oxaloacetate via pyruvate carboxylase.

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