Question

What is the most common heritable thrombosis risk factor in caucasians? A. Apc resistance (factor v leiden mutation) b. Prothrombin g20210a mutation c. Antithrombin deficiency d. Protein s deficiency

Answer 1

The second most common inherited risk factor for thrombosis is a point mutation (G20210A) in the 3' untranslated region of the prothrombin gene. This mutation is present in approximately 2% of healthy individuals and in 6-7% of thrombosis patients, suggesting it to be a mild risk factor of thrombosis