what is the number of chromosomes in human being ? what are genes and where are they located ?
Answers
Answer:
Chromosomes are structures within cells that contain a person's genes. Genes are contained in chromosomes, which are in the cell nucleus. A chromosome contains hundreds to thousands of genes. Every normal human cell contains 23 pairs of chromosomes, for a total of 46 chromosomes.
The total complement of genes in an organism or cell is known as its genome, which may be stored on one or more chromosomes. A chromosome consists of a single, very long DNA helix on which thousands of genes are encoded. The region of the chromosome at which a particular gene is located is called its locus.
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Explanation:
Chromosome Map
Publication Details
Image karyogram.jpg
Our genetic information is stored in 23 pairs of chromosomes that vary widely in size and shape. Chromosome 1 is the largest and is over three times bigger than chromosome 22. The 23rd pair of chromosomes are two special chromosomes, X and Y, that determine our sex. Females have a pair of X chromosomes (46, XX), whereas males have one X and one Y chromosomes (46, XY). Chromosomes are made of DNA, and genes are special units of chromosomal DNA. Each chromosome is a very long molecule, so it needs to be wrapped tightly around proteins for efficient packaging.
Near the center of each chromosome is its centromere, a narrow region that divides the chromosome into a long arm (q) and a short arm (p). We can further divide the chromosomes using special stains that produce stripes known as a banding pattern. Each chromosome has a distinct banding pattern, and each band is numbered to help identify a particular region of a chromosome. This method of mapping a gene to a particular band of the chromosome is called cytogenetic mapping. For example, the hemoglobin beta gene (HBB) is found on chromosome 11p15.4. This means that the HBB gene lies on the short arm (p) of chromosome 11 and is found at the band labeled 15.4.
With the advent of new techniques in DNA analysis, we are able to look at the chromosome in much greater detail. Whereas cytogenetic mapping gives a bird's eye view of the chromosome, more modern methods show DNA at a much higher resolution. The Human Genome Project aims to identify and sequence the ~30,000 genes in human DNA.
Chromosome 1
Contains over 3000 genes
Contains over 240 million base pairs, of which ~90% have been determined
See the diseases associated with chromosome 1 in the MapViewer.
Image a01chr.jpg
Chromosome 2
Contains over 2500 genes
Contains over 240 million base pairs, of which ~95% have been determined
See the diseases associated with chromosome 2 in the MapViewer.
Image a02chr.jpg
Chromosome 3
Contains approximately 1900 genes
Contains approximately 200 million base pairs, of which ~95% have been determined
See the diseases associated with chromosome 3 in the MapViewer.
Image a03chr.jpg
Chromosome 4
Contains approximately 1600 genes
Contains approximately 190 million base pairs, of which ~95% have been determined
See the diseases associated with chromosome 4 in the MapViewer
Image a04chr.jpg
Chromosome 5
Contains approximately 1700 genes
Contains approximately 180 million base pairs, of which over 95% have been determined
See the diseases associated with chromosome 5 in the MapViewer.
Image a05chr.jpg
Chromosome 6
Contains approximately 1900 genes
Contains approximately 170 million base pairs, of which over 95% have been determined
See the diseases associated with chromosome 6 in the MapViewer.
Image a06chr.jpg
Chromosome 7
Contains approximately 1800 genes
Contains over 150 million base pairs, of which over 95% have been determined
See the diseases associated with chromosome 7 in the MapViewer.
Image a07chr.jpg
Chromosome 8
Contains over 1400 genes
Contains over 140 million base pairs, of which over 95% have been determined
See the diseases associated with chromosome 8 in the MapViewer.
Image a08chr.jpg
Chromosome 9
Contains over 1400 genes
Contains over 130 million base pairs, of which over 85% have been determined
See the diseases associated with chromosome 9 in the MapViewer.
Image a09chr.jpg
Chromosome 10
Contains over 1400 genes
Contains over 130 million base pairs, of which over 95% have been determined
See the diseases associated with chromosome 10 in the MapViewer.
Image a10chr.jpg
Chromosome 11
Contains approximately 2000 genes
Contains over 130 million base pairs, of which over 95% have been determined
See the diseases associated with chromosome 11 in the MapViewer.
Image a11chr.jpg
Chromosome 12
Contains over 1600 genes
Contains over 130 million base pairs, of which over 95% have been determined
See the diseases associated with chromosome 12 in the MapViewer.
Image a12chr.jpg
Chromosome 13
Contains approximately 800 genes
Contains over 110 million base pairs, of which over 80% have been determined
See the diseases associated with chromosome 13 in the MapViewer.
Image a13chr.jpg
Chromosome 14
Contains approximately 1200 genes
Contains over 100 million base pairs, of which over 80% have been determined
See the diseases associated with chromosome 14 in the MapViewer.
Image a14chr.jpg
Chromosome 15
Contains approximately 1200 genes
Contains approximately 100 million base pairs, of which over 80% have been determined
See the diseases associated with chromosome 15 in the MapViewer.
Image a15chr.jpg
Chromosome 16
Contains approximately 1300 genes
Contains approximately 90 million base pairs, of which over 85% have been determined