What is the primary driving force for the binding of oxygen to hemoglobin?
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The following physiological factors influence the affinity of haemoglobin for oxygen:
The partial pressure of CO2 Increasing CO2 shifts the curve to the right. ...
pH, independent of CO2 ...
The concentration of 2,3-DPG inside the erythrocytes. ...
The presence of unusual haemoglobin species. ...
Temperature.
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