Question

What is the reason for the discontinuous synthesis of DNA on one of the parental strands?

Answer 1

the DNA synthesis occurs in 5’-3’ direction. The DNA strands act as templates. One of the strands is synthesized in the 3’-5’ direction. The other strand is synthesized in the opposite direction producing small stretches of DNA known as Okazaki fragments. That is why DNA synthesis is discontinuous.

Answer 2

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Synthesis of the lagging strand is more complicated because DNA polymerases can add nucleotides only to the 3 end of a primer or growing DNA strand.

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