Question

what is the reason for the formation of different charges on either side of the plasma membrane ?​

Answer 1

Answer:

The formation of different charges on either side of the plasma membrane is Because the inner and outer leaflets of the plasma membrane carry different charged lipids, the zeta potential at the extracellular and intracellular side also differ (24, 26). An alternative definition of the transmembrane potential is the difference in these two surface potentials (25)

Answer 2

Typical values of membrane potential are in the range –40 mV to –70 mV. The uncompensated positive charges outside the cell, and the uncompensated negative charges inside the cell, physically line up on the membrane surface and attract each other across the lipid bilayer.