Question

What is the role of histamine in inflammatory response?

Answer 1

Answer:

Histamine has the following roles during inflammatory responses:

1. Histamine is secreted from the mast cells, enterochromafin cells ,etc.

2. It is marked vasodilator ,i.e it dilates the blood vessels.

3. Histamine also increases the local blood pressure at the region of injury during inflammation. This leads to higher blood flow and redness during inflammation.

4. Finally, due to increase in local capillary hydrostatic pressure, fluid exudates (moves out) out of the blood vessel and accumulates in the interstitial space . This causes edema.

So Histamine is responsible for the cardinal signs of inflammation

1. Palor - paleness

2. Calor - heat

3. Rubor - redness

4. Tumor - swelling

5. Edema - accumulated fluid.

Answer 2

Answer:

$Histamine is involved in the inflammatory response and has a central role as a mediator of itching. ...Histamine increases the permeability of the capillaries to white blood cells and some proteins, to allow them to engage pathogens in the infected tissues.</p><p></p><p>Chemical formula: C5H9N3</p><p></p><p>Solubility in other solvents: Easily soluble in methanol. Very slightly soluble in diethyl ...</p><p></p><p>Solubility in water: Easily soluble in cold water, hot water</p><p></p><p>$