Question

What is the role of histamine in inflammatory response? Name two drugs?

Answer 1

Histamine is involved in the inflammatory response and has a central role as a mediator of itching. As part of an immune response to foreign pathogens, histamine is produced by basophils and by mast cells found in nearby connective tissues.

2 anti histamine drugs are:

Brompheniramine (Dimetane)

Cetirizine (Zyrtec)

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Answer 2

Role of histamine :

Histamine is a chemical which stimulates the secretion of pepsin and hydrochloric acid in the stomach. It causes inflammation in the body.

Histamine has the following functions

• It contracts the smooth muscles in the bronchi and gut, and relaxes other muscles.

• It is responsible for the nasal congestion associated with common cold and allergic responses to pollen.

Two drugs

• Asprin

• Phenelzine

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