What is the source of amino group for amino acid synthesis in reductive amination reaction?
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The source of amino group for amino acid:
Explanation:
- Reductive amination is process or preparing an amino acid from a carboxylic acid group by ammonia or ammonium ion.
- For example, glutamine is prepared from glutamate and ammonium ion. Here the amino group donor is ammonium ion.
- At first, the ammonia and carboxylic group reacts as acid-base reaction to form a salt.
- Then, oxygen of carboxylic group and hydrogen of ammonia leave as water, rendering the molecule to form a keto – imine tautomerism.
- This is acts upon by enzyme to form final amino acid.
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