Question

what is the status of the genome during cell differentiation

Answer 1

$\huge{\mathbb{\red{ANSWER}}}$

During the differentiation of pluripotent cells such as embryonic stem (ES) cells, pluripotency-associated genes are repressed, potentially permanently, as a result of DNA methylation. At the same time, developmental genes begin to be expressed, and there is an increase in H3K4 methylation.

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Answer 2

Answer:

During the differentiation of pluripotent cells such as embryonic stem (ES) cells, pluripotency-associated genes are repressed, potentially permanently, as a result of DNA methylation. At the same time, developmental genes begin to be expressed, and there is an increase in H3K4 methylation.