What is the striking feature of tRNA bases? How do these bases arise and what is their role?
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The tRNA or the transfer RNA have primary structures, secondary structure, and tertiary structure.
The secondary structure is the shape of a clover leaf with 3 unpaired amino acids - CCA. The anti-codon region has 3 amino acids bases, which are complementary to mRNA codon region bases. The 3rd nucleotide of the codon is called as the wobble base that allows wobble pairing in between the codon and the anticodon.
Each amino acid has a specific tRNA-synthetase which help in the esterification reactions.
The anticodon of the tRNA bind to the mRNA codon at the vacant an aminoacyl binding site (A site) and it is repeated for the next mRNA to form a polypeptide chain. Since the P-site and the A-site are close, a stable polypeptide chain if usually formed. This complex process called translocation is catalyzed by the peptidyl transferases.
The secondary structure is the shape of a clover leaf with 3 unpaired amino acids - CCA. The anti-codon region has 3 amino acids bases, which are complementary to mRNA codon region bases. The 3rd nucleotide of the codon is called as the wobble base that allows wobble pairing in between the codon and the anticodon.
Each amino acid has a specific tRNA-synthetase which help in the esterification reactions.
The anticodon of the tRNA bind to the mRNA codon at the vacant an aminoacyl binding site (A site) and it is repeated for the next mRNA to form a polypeptide chain. Since the P-site and the A-site are close, a stable polypeptide chain if usually formed. This complex process called translocation is catalyzed by the peptidyl transferases.
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