Question

what is the use of ion pair buffers in HPLC ​

Answer 1

Answer:

Ion Pair Chromatography is a method for improving the separation of charged analytes. In the resolution of organic ions with conventional HPLC methods, use of ion pair reagents can enhance peak shape and retention time when common remedies such as modifying eluent ratios or changing stationary phase fail.

Answer 2

Answer:

Ion Pair Chromatography is a method for improving the separation of charged analytes. In the resolution of organic ions with conventional HPLC methods, use of ion pair reagents can enhance peak shape and retention time when common remedies such as modifying eluent ratios or changing stationary phase fail. Figure 1.

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