Question

what is total no of chiral carbon in ranitidine and cemitidine​

Answer 1

There are a total of 13 chiral carbons in ranitidine.

Cimetidine contains a total of three chiral carbons.

Chiral carbon:

• In general, chiral carbon centres are four different substituents attached to carbon atoms that are located at the corners of a tetrahedron.
• Chiral carbon atoms are also referred to as "stereogenic carbons" and "asymmetrical carbon atoms."
• Finding chiral carbons requires looking for carbons with four different substituents.
• Any carbons with double bonds or two hydrogen atoms attached to them can be instantly removed.

Ranitidine:

• A medication that is sold under the brand names Zantac and others, ranitidine is used to reduce the production of stomach acid.
• It is often used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome.
• It can be given intravenously, intramuscularly, or orally.

Cimetidine:

• Cimetidine, a histamine H2 receptor antagonist, is marketed under the trade name Tagamet among others and reduces the formation of stomach acid.
• Heartburn and peptic ulcers are its two main uses.

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