Question

What is ultrafiltration?????

Answer 1

ultrafiltration occurs at the barrier between the blood and the filtratein the glomerular capsule (Bowman's capsule) in the kidneys. As in nonbiological examples of ultrafiltration, pressure (in this case blood pressure) and concentration gradients lead to a separation through a semipermeable membrane (provided by the podocytes). The Bowman's capsule contains a dense capillarynetwork called the glomerulus. Blood flows into these capillaries through the afferent arterioles and leaves through the efferent arterioles.

The high hydrostatic pressure forces small molecules in the tubular fluid such as water, glucose, amino acids, sodium chloride and urea through the filter, from the blood in the glomerular capsule across the basement membrane of the Bowman's capsule and into the renal tubules. This process is called ultrafiltration; the resulting fluid, virtually free of large proteins and blood cells, is referred to as glomerular filtrate, or ultrafiltrate.[1] Further modification of ultrafiltrate, by reabsorptionand secretion, transforms it into urine.

Glomerular pressure is about 75 millimeters of mercury (10 kPa). It is opposed by osmotic pressure (30 mmHg, 4.0 kPa) and hydrostatic pressure (20 mmHg, 2.7 kPa) of solutes present in capsular space. This difference in pressure is called effective pressure (25 mmHg, 3.3 kPa).

In hemodialysis centers, ultrafiltration takes place on the hemodialysis machines when the venous pressure is greater than the transmembrane pressure (TMP). This cleans whole blood while keeping its blood cellsintact.

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Answer 2

Ultrafiltration (UF) is a membrane filtration process similar to Reverse Osmosis, using hydrostatic pressure to force water through a semi-permeable membrane