what is ultrafiltration? how does it occurs
Answers
In renal physiology, ultrafiltration occurs at the barrier between the blood and the filtrate in the glomerular capsule (Bowman's capsule) in the kidneys. ... Blood flows into these capillaries through the afferent arterioles and leaves through the efferent arterioles.
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In renal physiology, ultrafiltration occurs at the barrier between the blood and the filtratein the glomerular capsule (Bowman's capsule) in the kidneys. As in nonbiological examples of ultrafiltration, pressure (in this case blood pressure) and concentration gradients lead to a separation through a semipermeable membrane (provided by the podocytes). The Bowman's capsule contains a dense capillarynetwork called the glomerulus. Blood flows into these capillaries through the afferent arterioles and leaves through the efferent arterioles.
The high hydrostatic pressure forces small molecules in the tubular fluid such as water, glucose, amino acids, sodium chloride and urea through the filter, from the blood in the glomerular capsule across the basement membrane of the Bowman's capsule and into the renal tubules. This process is called ultrafiltration; the resulting fluid, virtually free of large proteins and blood cells, is referred to as glomerular filtrate, or ultrafiltrate. Further modification of ultrafiltrate, by reabsorptionand secretion, transforms it into urine.