Question

what is Williamson synthesis process ?? ​

Answer 1

The Williamson ether synthesis is an organic reaction, forming an ether from an organohalide and a deprotonated alcohol (alkoxide). This reaction was developed by Alexander Williamson in 1850.Typically it involves the reaction of an alkoxide ion with a primary alkyl halide via an SN2 reaction. This reaction is important in the history of organic chemistry because it helped prove the structure of ethers.

synthesis :-

Named after:-

Alexander William Williamson

Reaction type:-

Coupling reaction

Identifiers:-

Organic Chemistry Portal:-

williamson-synthesis

RSC ontology ID:-

RXNO:0000090

An example is the reaction of sodium ethoxide with chloroethane to form diethyl ether and sodium chloride:

[Na]+[C2H5O]− + C2H5Cl → C2H5OC2H5 + [Na]+[Cl]−

This method is suitable for the preparation of a wide variety of unsymmetric ethers. The nucleophilic substitution of halides with alkoxides leads to the desired products.

If the halides are sterically demanding and there are accessible protons in the β-position, the alkoxide will act as a base, and side products derived from elimination are isolated instead.

The Williamson ether synthesis is an organic reaction used to convert an alcohol and an alkyl halide to an ether using a base such as NaOH. The mechanism begins with the base abstracting the proton from the alcohol to form an alkoxide intermediate. The alkoxide then attacks the alkyl halide in a nucleophilic substi-tution reaction (SN2), which results in the formation of the final ether product and a metal halide by-product

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Answer 2

here's the answer. hope this helps.