What is Xenobiotic stress?
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The constitutive androstane receptor (CAR, NR1I3) is a central regulator of xenobiotic metabolism. CAR activation induces hepatic expression of detoxification enzymes and transporters and increases liver size. Here we show that CAR-mediated hepatomegaly is a transient, adaptive response to acute xenobiotic stress.
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Xenobiotic - Wikipedia
A xenobiotic is a chemical substance found within an organism that is not include increased expression in genes involved in stress response and antibiotic resistance, changes in .
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