What limits the effects of neurotoxins on hippocampus?
Answers
Phthalates are synthetic derived chemicals which are used as plasticizers in various household products. They are not chemically bound by chemical polymers and over time, they migrate easily to these products and the environment. Evaluating the biological effect of phthalate exposure on developing organisms is experimental investigation that estimates of phthalate exposure in infants and children are significantly higher compared to adults. The extensive development and restructuring of neurokirkutri occurs during development, due to which the brain is susceptible to environmental insults. This evaluation reviews the result of phthalate exposure on the brain structure and task with special emphasis on the development aspects of hippocampal structural and functional plasticity. Generally, it appears that extensive interference in functional and structural plasticity of hippocampal occurs after exposure to the phthalates (formerly, peri- and post-natal). Regardless of whether these changes occur in direct neurotoxic effects of phthalates or indirect endocrine function through interference in the form of indirect effects, it is not fully understood. Wide-ranging examination that needs the assessment of phthalate exposure neurodevelopmental, neurotoxic neurondokrine and behavior association to offer an occasion to fully assess the neurotoxic potential of phthalates all through the life
Snakebite is classified by the WHO as a neglected tropical disease. Envenoming is a significant public health problem in tropical and subtropical regions. Neurotoxicity is a key feature of some envenomings, and there are many unanswered questions regarding this manifestation. Acute neuromuscular weakness with respiratory involvement is the most clinically important neurotoxic effect. Data is limited on the many other acute neurotoxic manifestations, and especially delayed neurotoxicity. Symptom evolution and recovery, patterns of weakness, respiratory involvement, and response to antivenom and acetyl cholinesterase inhibitors are variable, and seem to depend on the snake species, type of neurotoxicity, and geographical variations. Recent data have challenged the traditional concepts of neurotoxicity in snake envenoming, and highlight the rich diversity of snake neurotoxins.