Question

what reacts with haemoglobin and causes toxic effect to our health ​

Answer 1

Answer:

The results suggest that phagocytes (resident macrophages and recruited neutrophils) produced activated oxygen species (O2⋅− and H2O2), which react with Hb and iron-EDTA to generate more-toxic species such as ferryl ion and ⋅OH

Answer 2

Explanation:

Hemoglobin is toxic to the human body. When the hemoglobin is encapsulated in the red blood cell it is a tetramer, but outside the red blood cell in the plasma it breaks into two dimers that travel through the blood steam quickly and create a toxicity in the kidneys. This is why hemoglobin must be modified by cross-linking or recombination.

Hemoglobin in the plasma causes the oncotic pressure to decrease but this can be prevented by increasing the concentration of the hemoglobin to 7 g/dl, stabilizing the oncotic pressure.

Hemoglobin removes the NO from the vessel walls causing vasoconstriction, shrinkage of the vessels.