Question

What were the drawbacks of Mendel law of inheritance?

Answer 1

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The factors (genes) determine the organism's traits, and are inherited from its parents. As the pair of chromosomes separate, each gamete only receives one of each factor. This Mendel called the Law of segregation. Mendelalso noted that versions of a gene could be either dominant or recessive

Answer 2

The drawbacks of Mendel law of inheritance

Explanation:

• Dominance did not occur in every case of contrasting characters.
• Blending type of inheritance may occur in many crosses.
• Sometimes two dominants come together to form co-dominance e.g. in blood group inheritance (MN group).
• Non-allelic gene interaction like epistasis, inhibiting factors, presence of complementary gene and additive factors etc.
• Linkages between different genes.
• Non-disjunctions (non-separation of homologous chromosomes) of
• chromosomes during the time of formation of gametes (i.e. during Meiosis).
• Multiple factor (gene), that may or may not be allelic, for a single trait (e.g. skin color, height and weight of human) and their inheritance.
• Pleiotropic effect of a gene i.e. a gene having influences on more than one trait.
• Allelism i.e. the presence of a series of alternative genes at a given locus in a chromosome.
• Differential penetrance power (complete or incomplete) and expressivity of a given gene in different time.
• Presence of a lethal gene, i.e. an allele of a gene that renders inviable an organism.
• Differential environmental influences on the genetic effect of a particular pheno- type.
• Sex-linked genes i.e. the genes present in the ‘X’ or ‘Y’ chromosomes.
• Position effects of the gene, i.e. a single gene may have differential activity or expression in different positions in a single chromosome.
• Atavism, i.e. a gene comes to expression after a long period of non-expression because of the presence of different mask­ing effects.
• Presence of phenocopy, i.e. the similarity between the phenotype of a particular genotype trait with the phenotype of another genotype

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