What were the drawbacks of the earliest form of vaccination against smallpox that was available to the people?
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A recently completed scientific study has highlighted concern that there is a small but significant risk that individuals who receive a vaccination may spread infection to unvaccinated people
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There are certain drawbacks with the use of smallpox vaccination.
It is not possible to develop vaccines for organisms that are not grown in a culture.
The yield on the vaccines is quite small.Maintaing cell cultures is costly.
There remains a possibility of non-virulent organisms getting converted to virulent ones.
It is not possible to prevent diseases like AIDs using small pox vaccination.
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