Question

What will happen if islets of Langerhans fails to function? 

*CONTENT QUALITY ANSWER*

Answer 1

HEYA!!!!!

Today it was asked in my boards.

Here is your answer :
______________________________

=> Islets of Langerhans are present in pancreas in our body.

=> These islets secretes a hormone called Insulin.

=> Insulin controls the sugar levels in our body.

=> If these islets stop secreting Insulin then the sugar levels in our body increases.

=> This can result to the disease called Diabetes.


HOPE THIS HELPS U...

Answer 2

>>>>HELLO MISS RADHIKA<<<<


First, let me tell you the following things:

Pancreas is a mixed gland, which secretes both enzymes and hormones.

Pancreatic juice is secreted as an enzyme by Pancreas, which is poured into the cavity of duodenum.


As an endocrine gland, three hormones are secreted by Pancreas by some specialized cells called the Islets of Langerhans.


These three hormones are:

=> Glucagon (secreted from the alpha-cells).

=> Insulin (secreted from the beta cells).

=> Somatostatin (secreted from the delta cells).


Now, the short answer is that, when the Islets of Langerhans fail to function, these hormones will no more be produced.

Function of Glucagon: Glucagon converts liver glycogen into glucose and mixes them with the blood.

Function of Insulin: Insulin facilitates the utilization of glucose by the body cells. Hence it decreases the blood sugar level.

Function of somatostatin: Somatostatin inhibits the secretion of Glucagon or Insulin.


If these are not produced, the following things happen:



#1. When secretion of Insulin is stopped, there may be a remarkable rise in the blood glucose (sugar) level. If so:

=> The patient feels thirsty because excess urine is excreted.

=> Excess amount of glucose is passed out through the urine.

=> Ketone bodies are found in the urine.

=> In extreme cases, this affects the patient's eyesight or vision.

=> Patient becomes weaker and weaker and loses body weight.



#2. When the secretion of Glucagon is stopped, there may be a fall in the blood sugar level. If so:

=> The brain may enter the state of coma for some time.

=> Patient may become unconscious anywhere.



#3. If Somatostatin is not secreted, Insulin and Glucagon will be produced in unexpected amounts. [There will be no problem then, if the Insulin and Glucagon is not secreted at all].



NOW,

What problems the patient might face if his/her Islets of Langerhans malfunctions:



Suppose he meets an emergency situation. In this case, adrenaline hormone is secreted from the adrenal medulla, which again stimulates the sympathetic nervous system.

Now, glycogen from the liver will be converted into glucose and excess amount of glucose will be transported to the muscles and blood (so that the patient may have more energy to meet the situation).

After the emergency situation is over, generally what happens is that, insulin is secreted in large amounts so that the glucose thus transported in the blood is converted to glycogen again and stored in the liver (so that the blood sugar does not rise further).

However, since his Islets of Langerhans is no more functioning, Insulin won't be produced and the patient will thus suffer from an extreme case of Diabetes mellitus which may even lead to death.


HOPE MY ANSWER IS SATISFACTORY...

THANKS!