what will happen if melanin is absense in our body?
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Melanin is a vital pigment producing compound responsible for determining the colour of skin and hair. A deficiency in melanin can lead to several disorders and diseases.
For example, a complete absence of melanin causes a condition called albinism. Melanin deficiency has previously been associated with various genetic abnormalities and congenital defects.
Some of the diseases associated with melanin include:
Albinism - There are almost ten different types of oculocutaneous albinism, conditions that are inherited in an autosomal recessive manner. This means both parents need to have been carriers of one copy of the mutated gene with the offspring receiving two copies.
The most common form is oculocutaneous albinism type 2 which is particularly common among people of African ethnicity and describes a reduction or absence of melanin in the hair, skin and eyes. The incidence of this type of albinism is around 1 in 10,000 among African Americans and 1 in 36, 000 among White Americans.
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In some African nations the incidence of this type of albinism may be as high as 1 in 2000.