Question

What will happen if there is a deficiency of endoplasmic reticulum​

Answer 1

Answer:

ER stress occurs when the capacity of the ER to fold proteins becomes saturated. ER stress may be caused by factors that impair protein glycosylation or disulfide bond formation, or by overexpression of or mutations in proteins entering the secretory pathway

Answer 2

Answer:

deficiencies in ER stress pathways, such as impairment of the branch or overly active signaling, impair folding capacity and insulin processing within the ER and suffice to trigger β-cell dysfunction and death