Question

What would the consequence of deleting telomerase from a human cell line?

Answer 1

In addition to gradual telomere shortening during cell division, the loss of telomere function can also occur as a result of stochastic events in which large blocks of telomeric repeat sequences are lost in a single rapid deletion even

Answer 2

If we delete telomerase from a human cell line, we will die eventually. Every time cell division occurs, chromosomes lose a small portion of it from the ends. The presence of telomerase ensures that this loss of DNA slows down every time cell division occurs.

Now imagine, if we remove telomerase from human cell, how long would we live!