When do microtubules attach to kinetochores?
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The mitotic cycle of chromosome separation is linked to two checkpoints in the cell cycle: breakdown of the nuclear envelope during late prophaseand attachment of the microtubules to the kinetochores of sister chromatids at the metaphase-anaphase transition.
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in metaphase microtubules start to attach to kinetochores after the end of metaphase we can see that all the chromosomes are arranged on single plane with the help of microtubules
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