When fluoride concentration in water exceeds 1.5 ppm
or so, the disease that may be caused is:
(1) Methaemoglobinemia (2) Fluorosis
(3) Dental caries in children (4) Poliomyelitis
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At levels between 1.00–1.50 ppm, fluoride ions prevent dental caries by allowing the formation of strong calcium phosphate matrices in teeth and bones. At moderate levels between 1.50–4.60 ppm, they lead to dental fluorosis in children, whereas in high levels, it disrupts the mineralization of bones, leading to skeletal fluorosis.10,11The “optimum” or recommended level of fluoride in drinking-water, associated with the maximum level of dental caries protection and minimum level of dental fluorosis, is considered to be approximately 1 ppm.
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At levels between 1.00–1.50 ppm, fluoride ions prevent dental caries by allowing the formation of strong calcium phosphate matrices in teeth and bones. At moderate levels between 1.50–4.60 ppm, they lead to dental fluorosis in children, whereas in high levels, it disrupts the mineralization of bones, leading to skeletal fluorosis.10,11The “optimum” or recommended level of fluoride in drinking-water, associated with the maximum level of dental caries protection and minimum level of dental fluorosis, is considered to be approximately 1 ppm.
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