When kolbe's reaction takes place , why the major product is o-hydoxy benzoic acid?
Answers
Answered by
4
The Kolbe-Schmitt reaction proceeds via the nucleophilic addition of a phenolate to carbon dioxide to give the salicylate
the intermediate formed is more stable when the negative charge is held in the ortho position, as you have an electron withdrawing oxygen atom present on the adjacent carbon atom. Kolbe's reaction depends on the stability of the intermediate formed, and as the ortho giving intermediate is more stable the final product is ortho.
the intermediate formed is more stable when the negative charge is held in the ortho position, as you have an electron withdrawing oxygen atom present on the adjacent carbon atom. Kolbe's reaction depends on the stability of the intermediate formed, and as the ortho giving intermediate is more stable the final product is ortho.
Similar questions