where does the enzyme telomerase act?
Answers
Answer:
Cancer and Development
Telomerase is a specialized ribonucleoprotein polymerase that synthesizes the TAG telomeric repeats found at the end of chromosomes to maintain the length of the telomere. Thisenzyme is expressed in germ line cells but not in the majority of somatic cells.
Hii Mate Here Ur Answer ☑️↓↓↓
Telomerase is a ribonucleoprotein complex that maintains chromosome ends. It is a cellular reverse transcriptase composed of both RNA and proteins that employs its internal RNA component as a template for the synthesis of telomeric DNA. It stabilizes telomere length by adding hexameric (TTAGGG)n repeats onto telomeric ends of chromosomes. After adding six bases, the enzyme is believed to pause while it repositions (translocates) the template RNA in order to synthesize the subsequent 6 bp repeat. This extension of the 3′ DNA template end in turn allows replication of the 5′ end of the lagging strand. It thus compenshates for the continued erosion of telomeres and has been referred to as a ‘cellular immortalizing enzyme.’