where does the formation of acetyl coA takes place in cell
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Acetyl-CoA is generated either by oxidative decarboxylation of pyruvate from glycolysis, which occurs in mitochondrial matrix, by oxidation of long-chain fatty acids, or by oxidative degradation of certain amino acids. Acetyl-CoA then enters in the TCA cycle where it is oxidized for energy production.
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➡️mitochondria
In eukaryotic cells, the pyruvate molecules produced at the end of glycolysis are transported into the mitochondria, which are the sites of cellular respiration. There, pyruvate is transformed into an acetyl group that will be picked up and activated by a carrier compound called coenzyme A (CoA).
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