Where humidification of air takes place?
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ᴛʜᴇ ᴍᴏɪsᴛᴜʀᴇ ɪɴ ᴛʜᴇ ɴᴏsᴇ ʜᴇʟᴘs ᴛᴏ ʜᴇᴀᴛ ᴀɴᴅ ʜᴜᴍɪᴅɪғʏ ᴛʜᴇ ᴀɪʀ, ɪɴᴄʀᴇᴀsɪɴɢ ᴛʜᴇ ᴀᴍᴏᴜɴᴛ ᴏғ ᴡᴀᴛᴇʀ ᴠᴀᴘᴏᴜʀ ᴛʜᴇ ᴀɪʀ ᴇɴᴛᴇʀɪɴɢ ᴛʜᴇ ʟᴜɴɢs ᴄᴏɴᴛᴀɪɴs. ᴛʜɪs ʜᴇʟᴘs ᴛᴏ ᴋᴇᴇᴘ ᴛʜᴇ ᴀɪʀ ᴇɴᴛᴇʀɪɴɢ ᴛʜᴇ ɴᴏsᴇ ғʀᴏᴍ ᴅʀʏɪɴɢ ᴏᴜᴛ ᴛʜᴇ ʟᴜɴɢs ᴀɴᴅ ᴏᴛʜᴇʀ ᴘᴀʀᴛs ᴏғ ᴏᴜʀ ʀᴇsᴘɪʀᴀᴛᴏʀʏ sʏsᴛᴇᴍ. ... ɪᴛ ɪs ɢᴇɴᴇʀᴀʟʟʏ ʙᴇᴛᴛᴇʀ ᴛᴏ ᴛᴀᴋᴇ ɪɴ ᴀɪʀ ᴛʜʀᴏᴜɢʜ ᴛʜᴇ ɴᴏsᴇ.
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Humidification of air takes place in the nose.
- The main function of the nose is to warm and humidify the air before it reaches the lungs for gas exchange. Conditioning of the stimulated air is done through evaporation of water from the epithelial surface.
- The uninterrupted need to condition the air advances to a hyper-osmolar environment on the surface of the epithelium. As airing grows, the hyper-osmolar surface moves more distally, cowling a bigger surface area of the airway, and stimulating epithelial cells to set free the mediators that lead to inflammation.
- This inflammation causes both short-term and long-term changes in the epithelium. In the short term, it advances paracellular water transport so as to enhance conditioning, and it also stimulates sensory nerves to initiate neural reflexes. It also causes disruption in the channels of the cellular membrane, which might permit larger penetration of foreign proteins, such as allergens, leading to further inflammatory cascades.
- The long-term inflammation induced over time by the hyper-osmolar milieu could worsen the ability of the nose to condition air, requiring more conditioning to occur in the lower airway and leading to adverse consequences for the respiratory system.
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