Which base is used to abstract carboxylic acid proton?
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When the compound is not particularly acidic, and, as such, the molecule does not give up its proton easily, a base stronger than the commonly known hydroxides is required. Hydrides are one of the many types of powerful deprotonating agents. Common hydrides used are sodium hydride and potassium hydride.
Deprotonation (or dehydronation) is the removal (transfer) of a proton (or hydron, or hydrogen cation), (H+) from a Brønsted–Lowry acid in an acid-base reaction. ... The complementary process, when a proton is added (transferred) to a Brønsted–Lowry base, is protonation (or hydronation).
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